Role of Wnt/Β-Catenin Signaling in Regulating the Balance between Oxidative Stress and Apoptosis in Peripheral Blood Mononuclear Cells from Patients with Facioscapulohumeral Muscular Dystrophy
نویسندگان
چکیده
Facioscapulohumeral dystrophy (FSHD) is the third most common type of muscular dystrophy after Duchenne and myotonic dystrophy with an incidence of 12 per 100,000 worldwide [1,2]. FSHD is an autosomal dominant disease with an insidious onset and development, characterized by progressive weakness and atrophy of facial, shoulder girdle and upper arm muscles [1]. Currently FSHD diagnosis is mainly based on clinical evaluation, often supported by a genetic confirmation.
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